The SPYDER (Surface-to-air PYthon and DERby) is an anti-aircraft missile system developed by Rafael Advanced Defense Systems (with use of Czech Tatra chassis) and using surface-to-air versions of the Python 5 and Derby missiles, also made by Rafael Advanced Defense Systems.

It is a quick reaction medium range missile system. SPYDER is capable of engaging aircraft, helicopters, unmanned air vehicles, drones and precision-guided munitions. It provides air defence for fixed assets and for point and area defence for mobile forces in combat areas. The SPYDER-SR system has 360° engagement capability and the missiles can be launched from the full-readiness state in less than five seconds from target confirmation. The kill range is up to 20 miles and at altitudes from a minimum of 50 ft to a maximum of 120, 000 ft. The system is capable of multi-target simultaneous engagement and also single, multiple and ripple firing, by day and night and in all weathers.